GHS Hazard Statements

GHS Hazard Statements

Complete List of GHS Hazard Statements and Their Meaning

Understanding chemical hazards starts with understanding the standardized language used to describe them. Under the Globally Harmonized System (GHS), hazard communication ensures that workers, employers, and emergency responders receive consistent and clear safety information no matter where chemicals are manufactured or used. In the United States, OSHA implements GHS principles through the Hazard Communication Standard (HCS), 29 CFR 1910.1200.


One of the most important components of this system is the hazard statement.


GHS uses a uniform approach to classify chemicals and communicate hazards on labels and Safety Data Sheets (SDS). Every U.S.-compliant GHS label must contain six specific elements that work together to communicate risk:


Each element has a purpose. The hazard statement is the part of the label that clearly communicates what hazard is present and how severe it is. Hazard statements guide which pictograms appear, which signal word is used, and what precautions apply.

What is a GHS Hazard Statement?

A hazard statement is a required, standardized phrase that describes the type and severity of a chemical hazard. It is not a general warning or a guideline. It is tied directly to the chemical’s official classification.


GHS hazard statements must:


  • Appear exactly as written in OSHA’s Hazard Communication Standard

  • Be included on all shipped container labels

  • Be listed in Section 2 of the SDS

  • Match the chemical’s GHS hazard class and category

  • Communicate hazards in clear, universally recognized language

These statements remove ambiguity and make hazards easy for workers to understand.

Determining a Chemical’s Hazard Statement

To determine which hazard statement applies to a chemical, you need to understand its GHS classification. This classification is normally done by the manufacturer or importer, but employers should understand the basics so they can read labels correctly and maintain compliance.


Two elements determine the hazard statement:


1. GHS Hazard Class - This identifies the type of hazard, such as flammable liquid, skin irritation, respiratory sensitization, or carcinogenicity. A chemical can have several hazard classes.


2. GHS Hazard Category - This identifies the severity of the hazard within the class. Categories range from 1 (most severe) to 4 (least severe), depending on the hazard class.


Each class and category pairing has one specific hazard statement. OSHA requires that hazard statements be used exactly as published with no rewriting or combining.


For U.S. workplaces, the required hazard statements appear in:


  • Section 2: Hazard Identification of the supplier’s SDS

  • The manufacturer’s or importer’s GHS-compliant shipped label

If a chemical is transferred to a secondary container for use beyond immediate use, employers must use the same hazard statements shown in Section 2 of the SDS or on the shipped label.


Businesses that want additional context can review OSHA Hazard Communication Standard Appendix C for the official U.S. list of required hazard statements or the UN GHS “Purple Book” or global variations. OSHA’s standard is based on GHS Revision 3.

Structure of GHS Hazard Statements

GHS hazard statements follow a simple numbering system that helps you understand the type of hazard a chemical presents. Each statement begins with the letter H and a three-digit number. The first digit identifies the general hazard group.


  • H200–H299 identify physical hazards such as flammability, explosion, oxidizing ability, and reactivity.

  • H300–H399 identify health hazards such as toxicity, irritation, cancer effects, and organ toxicity.

  • H400–H499 identify environmental hazards such as aquatic toxicity.


For U.S. businesses, the important point is which groups OSHA enforces. Physical hazard statements in the H2 series and health hazard statements in the H3 series are required. Environmental hazard statements in the H4 series may appear on SDSs from global suppliers but are not required for U.S. workplace labeling except for the ozone depletion statement H420.


Some international documents may reference codes such as EUH001. These are specific to the European Union and are not used under OSHA’s Hazard Communication Standard.


Understanding this structure helps you interpret hazard statements more easily and identify which ones apply to OSHA compliance.

Physical Hazard Statements - H2 Codes

These statements describe flammability, explosiveness, oxidizing potential, pressure buildup, and other physical risks.

Code

Meaning Summary

H200
Unstable explosive
H201
Explosive; mass explosion hazard
H202
Explosive; severe projection hazard
H203
Explosive; fire, blast or projection hazard
H204
Fire or projection hazard
H205
May mass explode in fire
H206*
Fire, blast or projection hazard; increased risk of explosion if desensitizing agent is reduced
H207*
Fire or projection hazard; increased risk of explosion if desensitizing agent is reduced
H208*
Fire hazard; increased risk of explosion if desensitizing agent is reduced
H220
Extremely flammable gas
H221
Flammable gas
H222
Extremely flammable aerosol
H223
Flammable aerosol
H224
Extremely flammable liquid and vapour
H225
Highly flammable liquid and vapour
H226

Flammable liquid and vapour

H227

Combustible liquid

H228

Flammable solid

H229

Pressurized container: may burst if heated

H230*

May react explosively even in the absence of air

H231*

May react explosively even in the absence of air at elevated pressure and/or temperature

H232*

May ignite spontaneously if exposed to air

H240

Heating may cause an explosion

H241
Heating may cause a fire or explosion
H242
Heating may cause a fire
H250
Catches fire spontaneously if exposed to air
H251

Self-heating; may catch fire

H252
Self-heating in large quantities; may catch fire
H260
In contact with water releases flammable gases which may ignite spontaneously
H261
In contact with water releases flammable gas
H270
May cause or intensify fire; oxidizer
H271
May cause fire or explosion; strong oxidizer
H272
May intensify fire; oxidizer
H280
Contains gas under pressure; may explode if heated
H281
Contains refrigerated gas; may cause cryogenic burns or injury
H290
May be corrosive to metals

Health Hazard Statements - H3 Codes

These statements describe acute toxicity, irritation, sensitization, carcinogenicity, reproductive toxicity, and organ effects.

Code

Meaning Summary

H300
Fatal if swallowed
H301
Toxic if swallowed
H302
Harmful if swallowed
H303*
May be harmful if swallowed
H304
May be fatal if swallowed and enters airways
H305*
May be harmful if swallowed and enters airways
H310
Fatal in contact with skin
H311
Toxic in contact with skin
H312
Harmful in contact with skin
H313*
May be harmful in contact with skin
H314
Causes severe skin burns and eye damage
H315
Causes skin irritation
H316*
Causes mild skin irritation
H317
May cause an allergic skin reaction
H318

Causes serious eye damage

H319

Causes serious eye irritation

H320*

Causes eye irritation

H330

Fatal if inhaled

H331

Toxic if inhaled

H332

Harmful if inhaled

H333*

May be harmful if inhaled

H334

May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335

May cause respiratory irritation
H336
May cause drowsiness or dizziness
H340
May cause genetic defects
H341

Suspected of causing genetic defects

H350
May cause cancer
H351
Suspected of causing cancer
H360
May damage fertility or the unborn child
H361
Suspected of damaging fertility or the unborn child
H361d
Suspected of damaging the unborn child
H362
May cause harm to breast-fed children
H370
Causes damage to organs
H371
May cause damage to organs
H372
Causes damage to organs through prolonged or repeated exposure
H373
May cause damage to organs through prolonged or repeated exposure

Environmental Health Hazards - H4 Codes

These statements address aquatic toxicity and impacts to the environment. OSHA does not enforce most environmental hazard statements, but you may see them on SDSs from global suppliers.

Code

Meaning Summary

H400*
Very toxic to aquatic life
H401*
Toxic to aquatic life
H402*
Harmful to aquatic life
H410*
Very toxic to aquatic life with long-lasting effects
H411*
Toxic to aquatic life with long-lasting effects
H412*
Harmful to aquatic life with long-lasting effects
H413*
May cause long-lasting harmful effects to aquatic life
H420
Harms public health and the environment by destroying ozone in the upper atmosphere
H441*
Very toxic to terrestrial invertebrates

Hazard statements marked with * are global GHS hazard statements not adopted under OSHA's Hazard Communication Standard. These may appear on SDSs from international suppliers but are not required for U.S. workplace labeling.

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